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Thread: Sunlight the solution to diabetes?

  1. #1

    Default Sunlight the solution to diabetes?

    This very short article in today's Times makes interesting reading. It would, of course, be lovely to see more detail but the name of the researcher can always be googled later.
    Gilli - DLTBGYD but more importantly KCHO

  2. #2
    Super Member Mamie's Avatar
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    The comments make interesting reading.

  3. #3

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    “There are two possible explanations. The first is that this is an indirect effect; when the weather is better you spend more time outdoors exercising.

    “There could also be direct effects — we have to speculate here — and one mechanism could be vitamin D and the other we speculate is melatonin.”

    Instant confounder: People who are more health-conscious are more likely to spend time outdoors and exercise. Of course, they're also more likely to slather themselves with sunscreen which would cancel out any benefit from solar-generated vitamin D (though they're probably more likely to take vitamin D supplements)

  4. #4

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    Good points Hugh!
    Gilli - DLTBGYD but more importantly KCHO

  5. #5

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    While there is a lot more to sunlight than just vitamin d3 we should not forget that vitamin d is the regulator of the insulin degrading enzyme that also clears amyloid and glucagon.

    Bear in mind when you read vitamin d research most is done deliberately to produce null results.
    Cholecalciferol has a half-life in serum of just 24 hours and it's only at levels above 50ng/ml that we can measure free bio-available cholecalciferol in significant amounts in serum in most people, where it stabilises endothelial function and provides the signalling modality that inhibits inflammation. Therefore when we look at this rat study and see they used 20,000iu cholecalciferol by injection fortnightly we can assume they weren't being serious.
    If you want a signalling modality to turn on/off pro-inflammatory cytokine production we need it to work 24/7. Like the central heating. Switching it on or off once a fortnight is not the kind of heating control modality that is going to work.

    The Effect of Vitamin D on Cellular Pathways of Diabetic Nephropathy
    Vitamin D may reduce diabetic nephropathy not only by improving blood glucose and insulin levels, but also by modulating hexosamine pathways in kidney.
    The effect of vitamin D supplementation on glucose metabolism in type 2 diabetes mellitus: A systematic review and meta-analysis of intervention studies
    Which if any of these studies used NATURAL amounts of cholecalciferol daily to maintain DAILY CHOLECALCIFEROL levels in serum to enable regulation of inflammation throughout the 24 hours of the day EVERY DAY of the week.

    We also know that the presence of Magnesium is required to enable the enzyme reactions that activate vitamin d3. Role of Magnesium in Vitamin D Activation and Function
    Most people are vitamin d deficient/insufficient and the recommended dietary amounts are really set to low for magnesium.
    Subclinical magnesium deficiency: a principal driver of cardiovascular disease and a public health crisis
    Last edited by TedHutchinson; 5th March 2019 at 11:22 PM.

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    Supermember 2016-20 PerryPoole's Avatar
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    Thanks Ted!

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    Thank you Ted.

    Being ignorant about vits and minerals, why then is there a rise in people who live in much sunnier climates seeing an increase of diabetes in their population, as they taken on the worse of western lifestyles. There are certainly other factors playing a role with increasing diabetes e.g. urbanization means people are not undertaking hard physical work or exercising so much. Asian men in particular smoke more. Other reasons are given

    http://www.asiandiabetesprevention.o...ns-higher-risk

    So whilst sunlight and vit d may play a role this surely has to be set along side other factors.

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    Super Member roseymary's Avatar
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    In Australia, a slogan "Slip, slop, slap" which encouraged us to cover up and use sunscreen has seen people in a sunny country become vitamin D deficient.
    One is too many a thousand not enough.

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    Super Member Christelle's Avatar
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    It's the same here with us. People are encouraged to use sunscreen and to not be outside between 11:00 and 14:00
    Also, most of us now spend our days indoors working and not outside tending the lands
    Trust the process, the results will come

  10. #10

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    Quote Originally Posted by ChristineJ View Post
    So whilst sunlight and vit d may play a role this surely has to be set along side other factors.
    I'm not suggesting that lack of vitamin d and magnesium is the only factor driving diabetes/heart disease. But if you've been following Kendrick's Cause of Heart Disease series you will know that endothelial dysfunction and chronic inflammation appear right at the start of the disease process. Both of these are related to low vitamin d and low magnesium levels. Modern industrially produced and over processed foods have less magnesium and more pro-inflammatory ingredients. If you are religiously avoiding industrial seed/grain oil and all forms of sugar you'll know how impossible it is becoming.
    If we kept our vitamin d and magnesium intakes equivalent to those found in indigenous peoples we'd all delay the onset of these conditions.

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