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Thread: Statins not working

  1. #11
    Club Member Hugh Mannity's Avatar
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    Thanks Ted

    So, looking at the study, they don't report overall mortality -- which in the end is the only thing that matters. And I'm not sure that a decrease in CVD-related death from 1.6 per 1000 patient-years to 1.5 is worth the potential damage statins do.

  2. #12

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    And at the end of the article is the “amazing news” that there will be new medication to deal with this problem! Dr Malcolm said that as soon as statins were off patent, there would be a new, wonder drug, many pounds more expensive, and still under patent to take their place

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    Club Plus Member Sarah(sjc)'s Avatar
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    Aren't we a happy band of conspiracy theorists!!

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    Super Member Mamie's Avatar
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    Don’t you just love it Sarah?

  5. #15
    Club Member Hugh Mannity's Avatar
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    Quote Originally Posted by Vanna-C View Post
    And at the end of the article is the “amazing news” that there will be new medication to deal with this problem! Dr Malcolm said that as soon as statins were off patent, there would be a new, wonder drug, many pounds more expensive, and still under patent to take their place
    Ah yes, the PCSK9 inhibitors. Evolocumab (Repatha) has had its price reduced to a mere $5850, down from over $14,000 when it was first approved. Alirocumab (Praluent) is still around $14,000/year.

    Also, they're both injectables, so that means you'll be headed off to the doctor every couple of weeks to get your shot. Compliance will be much easier to enforce that way. (what conspiracy?)

  6. #16
    Club Plus Member Sarah(sjc)'s Avatar
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    Been having fun on BBC HYS for most of the day!

  7. #17

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    Quote Originally Posted by Hugh Mannity View Post
    Ah yes, the PCSK9 inhibitors. Evolocumab (Repatha) has had its price reduced to a mere $5850, down from over $14,000 when it was first approved. Alirocumab (Praluent) is still around $14,000/year.

    Also, they're both injectables, so that means you'll be headed off to the doctor every couple of weeks to get your shot. Compliance will be much easier to enforce that way. (what conspiracy?)
    And I believe that the trials were stopped early as cholesterol was indeed dropping*..... As were the intervention group**.....

    * Yay - the thing we wanted to measure dropped

    ** Shit! People are dying - Better stop the trial before too many do... We'll still sell the drug though as it works for what we were testing it for! Sod the unintended consequences of killing people..
    The worst bigots in the world are those who most loudly proclaim their ‘tolerance’

  8. #18
    Club Member Hugh Mannity's Avatar
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    Quote Originally Posted by Mat View Post
    And I believe that the trials were stopped early as cholesterol was indeed dropping*..... As were the intervention group**.....

    * Yay - the thing we wanted to measure dropped

    ** Shit! People are dying - Better stop the trial before too many do... We'll still sell the drug though as it works for what we were testing it for! Sod the unintended consequences of killing people..
    Yea. Stopping a trial early is a sure sign of shenanigans.

  9. #19
    Super Member Christelle's Avatar
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    But normally their excuse for doing this is: the people on the medication was doing just so brilliantly that not giving the medication to ALL in the study would be deemed unethical...
    Trust the process, the results will come

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