Results 1 to 5 of 5

Thread: Vitamin D and Covid-19

  1. #1
    Super Member roseymary's Avatar
    Join Date
    May 2014
    Location
    Melbourne Australia
    Posts
    14,110

    Default Vitamin D and Covid-19

    Vitamin D for COVID-19: a case to answer? From the Lancet.


    https://www.thelancet.com/journals/l...268-0/fulltext
    One is too many a thousand not enough.

  2. #2

    Default

    Thanks RM!
    The worst bigots in the world are those who most loudly proclaim their ‘tolerance’

  3. #3
    Club Member
    Join Date
    Jul 2016
    Location
    South Norfolk
    Posts
    4,079

    Default

    Thank you from me also. I am religiously taking mine, even though it is summer and I am in the garden more than indoors.

  4. #4
    Super Member roseymary's Avatar
    Join Date
    May 2014
    Location
    Melbourne Australia
    Posts
    14,110

    Default

    Christine - I take vit D supplements all year round even living in Australia, just a lower dose in summer 5000iu and double in winter.
    One is too many a thousand not enough.

  5. #5

    Default


    Article is rather spoilt by this section.
    Pending results of such trials, it would seem uncontroversial to enthusiastically promote efforts to achieve reference nutrient intakes of vitamin D, which range from 400 IU/day in the UK to 600–800 IU/day in the USA. These are predicated on benefits of vitamin D for bone and muscle health, but there is a chance that their implementation might also reduce the impact of COVID-19 in populations where vitamin D deficiency is prevalent; there is nothing to lose from their implementation, and potentially much to gain.
    Mean 25(OH)D levels in the UK and indeed much of the USA work out just under 50nmol/l 20ng/ml.
    To reduce the severity of covid requires level above 32ng/ml 80nmol/l.

    This is because as this paper explains Dietary Vitamin D and Its Metabolites Non-Genomically Stabilize the Endothelium the signalling modality required to enable the inhibition of proinflammatory cytokines requires the presence of CHOLECALCIFEROL in serum

    This chart shows the amount of cholecalciferol, the basic form of vitamin d3 that was thought to be inert, in relation to 25(OH)D status.


    Ideally to prevent a cytokine storm it's sensible to ensure 25(OH)D is kept around 50ng/ml 125nmopl/l as that is the level vitamin d3 cholecalciferol optimally inhibits the production of pro-inflammatory cytokines.

    How vitamin D inhibits inflammation
    "The highest levels of inflammatory inhibition occurred at 50 ng/ml."
    If you are a total idiot and think the LANCET is right to "enthusiastically promote efforts to achieve reference nutrient intakes of vitamin D, which range from 400 IU/day in the UK to 600–800 IU/day in the USA. " that's your choice but generally speaking to get from current 25(OH)D levels of around 50nmol/l 20 ng/ml to 125nmol/l 50ng/ml requires around 8000 iu vitamin d3 DAILY.

    That is the amount that actually works best in practice.

    Serum Level vs Intake
    To get above 100nmol/l 40ng/ml at this latitude generally requires 6000iu/d normal weight 7000iu/d for overweight and 8000iu/d for the obese from Evaluation of vitamin D3 intakes up to 15,000 international units/day

    It's sad that the Official rubbish recommended daily amounts keep being promoted.
    You would think they would know by now that taking just 800iu day is about as good as placebo.
    If you want to stay deficient take the recommended daily amount
    If you want a NATURAL HUMAN VITAMIN D LEVEL equivalent to the amounts measured in indigenous peoples living traditional outdoor lifestyles you need the amounts of vitamin d3 daily equivalent to near full body sun exposure.
    Last edited by TedHutchinson; 6th August 2020 at 09:55 AM.

Bookmarks

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •  
Single Sign On provided by vBSSO